化疗药物型栓塞剂介入治疗宫颈癌的临床探讨

Clinical Observation of Interventional Treatment with Chemotherapy Embolization Agent for Cervical Cancer

目的探讨使用化疗药物型栓塞剂介入栓塞治疗宫颈癌的疗效及不良反应。方法对该院于2010年1月—2013年12月收治的150例宫颈癌患者进行子宫动脉介入栓塞化疗,随机分为治疗组和对照组,治疗组采用化疗药物型栓塞剂栓塞;对照组采用化疗药物动脉灌注后再行碘油乳剂栓塞,其后均用大颗粒明胶海绵栓塞。总结分析近期疗效、骨髓抑制反应及主要胃肠道反应。结果治疗组有效率为82.50%,对照组有效率为84.29%,差异无统计学意义(P>0.05)。但对照治疗后骨髓抑制反应及主要胃肠道反应两组差异明显。结论使用化疗药物型栓塞剂的患者治疗后不良反应明显小于对照组,患者易于接受,而疗效与对照组无明显差别。

Objective To observe the efficacy and adverse reactions of interventional treatment with chemotherapy embolization agent for cervical cancer.Methods The 150 cases of cervical cancer patients with uterine artery embolization chemotherapy were randomly divided into treatment group and control group,the treatment group received chemotherapy embolization agent;the control group arterial infusion chemotherapy after the line lipiodol emulsion embolization are subsequendy gelfoam embolization with large particles.Summary analysis of short-term effect,bone marrow suppression response and major gastrointestinal reactions.Results Efficiency of the control group,82.50%,had no statistically significant difference with that,84.29%,of the treatment group（P〉0.05）,but the bone marrow suppression and major gastrointestinal effects of the the two groups were significant differences.Conclusion Adverse reactions in patients after treatment of chemotherapy embolization agent is significantly less than that in the patients of the control group,so this method is easily accepted for patients,but there was no significant difference in the efficacy of the two groups.