地佐辛联合丙泊酚应用于无痛人流的临床探讨

Clinical Observation of Dezocine Combined with Propofol Used in Painless Induced Abortion

目的探讨地佐辛联合丙泊酚静脉麻醉用于人工流产术的临床镇痛效果及安全性。方法随机选取该院于2012年9月—2013年10月间收治的健康早期妊娠,自愿要求人工流产的妇女300例为研究对象,并随机平均分成三组进行麻醉对照,其中A组100例,采用舒芬太尼+丙泊酚进行临床镇痛;B组100例,采用芬太尼+丙泊酚进行临床镇痛;C组100例,采用地佐辛+丙泊酚进行临床镇痛。比较三组临床镇痛效果。结果注药2 min后,血压、呼吸次数、脉搏血氧饱和度A组有所下降,B组基本无变化,C组大致在正常范围内,且A组患者苏醒时间为(6.45±0.51)min、B组患者苏醒时间为(6.34±0.54)min、C组患者苏醒时间为(4.73±0.44)min,C组患者苏醒时间要明显优于A组和B组,差异有统计学意义,P<0.05。结论丙泊酚联合地佐辛用于门诊无痛人流术临床镇痛效果显著,安全可行。

Objective To observe the clinical analgesic effect and safety of dezocine combined with propofol intravenous anesthesia used in artificial abortion.Methods 300 early pregnant women who was healthy and voluntarily required artificial abortion between September 2012 and October 2013 were selected as the research object and randomly divided into three groups of anesthesia control group,including 100 cases of A group,with sufentanil ＋ propofol for clinical analgesia;B group of 100 cases,using fentanyl ＋ propofol for analgesia use;100 cases in group C,dezocine ＋ propofol for analgesia.Clinical analgesic effects of them were compared.Results Note 2min after administration,blood pressure,respiratory frequency,pulse oxygen saturation decline in A group,B group did not change,the C group is roughly in the normal range,and the recovery time for patients in the A group（6.45±0.51） min,B group patients recovery time for（6.34 ±0.54） min,C group patients recovery time as（4.73 ±0.44） min,C group patients recovery time was significantly better than that of A group and B group,the difference was statistically significant,P〈0.05.Conclusion The effect of propofol combined with dezocine for outpatient painless abortion clinical analgesic is remarkable,so it is safe and feasible.