孟鲁司特治疗不同病原感染后毛细支气管炎的疗效

Effect of Montelukast Treatment on Bronchiolitis Induced by Different Etiological Agents

目的探讨孟鲁司特治疗不同病原感染后毛细支气管炎的疗效。方法该研究随机选取该院于2013年1月—2014年10月收治的100例不同病原感染后毛细支气管炎患者,将其分为腺病毒组和副流感病毒组,两组患者都采用孟鲁司特治疗方式,对比两组患者的病原性检测结果、住院时间、临床症状评分结果、临床疗效以及不良反应发生率结果。结果腺病毒组患者的住院时间、临床症状(咳嗽、哮鸣音以及喘息)评分结果分别是(7.42±2.34)d、(0.96±0.38)分、(0.76±0.98)分和(1.12±1.20)分,副流感病毒组患者的住院时间、临床症状(咳嗽、哮鸣音以及喘息)评分结果分别是(7.76±2.38)d、(1.01±0.45)分、(0.79±0.77)分和(1.14±1.17)分,两组结果对比差异无统计学意义(P>0.05)。结论采用孟鲁司特治疗不同病原感染后毛细支气管炎患者有很好的临床效果,尤其是对于副流感病毒感染引起的支气管炎患者有着显著疗效,能够有效的降低患者的不良反应发生率,使得患者早日出院,值得在临床上推广应用。

Objective To investigate the effect of montelukast treatment on bronchiolitis induced by different etiological agents.Methods This paper selected 100 patients with bronchiolitis induced by different etiological agents treated in our hospital between January 2013 and October 2014 as the research object and divided them into the adenovirus group and parainfluenza virus group.All of them received montelukast treatment.Pathogenic detection results,hospitalization time,symptom score results,clinical curative effect and adverse reaction were compared between the two groups.Results The adenovirus group patients hospitalization time,clinical symptoms（cough,wheezing andwheezing） score results are（7.42±2.34） days,（0.96±0.38）,（0.76±0.98） and（1.12＋1.20）,parainfluenza virus group patients hospitalization time,clinical symptoms shape（eough,wheezing and wheezing） score results are（7.76±2.38） days,（1.01±0.45）,（0.79±0.77） and（1.14±1.17）,the two sets of results compared no significant difference（P〉0.05）,has no statistical significance.Conclusion The use of montelukast in the treatment of differentpathogen infection bronchiolitis patients had good clinical effects,especially the causes for parainfluenza virusinfection bronchitis patients with obvious curative effect,can effectively reduce the incidence of adverse reaction of patients,making patients for early discharge,worth in clinical application.