尼莫地平对高血压脑出血治疗的研究

Analysis of Clinical Effect of Nimodipine in Treatment of Hypertensive Cerebral Hemorrhage

目的对尼莫地平用于高血压脑出血治疗的临床效果进行探讨分析。方法选取2012年8月—2014年8月于该院进行救治的498例高血压脑出血患者,将其随机分为观察组250例与对照组248例,其中对照组采用常规治疗,观察组在对照组的基础上,加用尼莫地平治疗。并且对治疗效果进行观察记录。结果观察组总有效率为92.4%,对照组总有效率为82.6%,明显低于观察组(x^2=8.4471,P<0.05);治疗后,观察组三项指标:血肿体积、水肿面积、神经功能评分均比对照组改善明显,各指标内相比差异有统计学意义(P<0.05);两组患者不良反应率差异无统计学意义(x^2=4.9381,P>0.05)。结论尼莫地平治疗高血压脑出血具有疗效好,不良反应低等优点。

Objective To investigate the application of nimodipine in treating Hypertensive Cerebral Hemorrhage.Methods 498in-patients with hypertensive cerebral hemorrhage treated in our hospital from August 2012 to August 2014 were selected and randomly divided into observation group and control group.248 patients in the control received routine treatment,while 250 patients in the observation group was given nimodipine injection based on routine treatment.The therapeutic effectiveness of the two groups was compared.Results The total efficiency of the observation group was 92.4%,which was higher than 82.6%of the control group（P〈0.05）;The absorption of hemorrhage,edema and ESS were better in the observation group（P〈0.05）;no obvious differences of adverse reaction were observed between the two groups（P〉0.05）.Conclusion Nimodipine injection in the treatment of patients with HCT has the advantages of remarkable effect and low incidence of adverse reaction,benefit for the absorption of hemorrhage and edema and the improvement of neurological function of patient,which should be widely applied in clinic.