腰椎间盘退变性疾病的研究进展

Research Progress of Lumbar Degenerative Disease

LDDD属于临床常见脊柱疾病,相关学者将其定义为,因腰椎间盘与关节突的关节软骨及周围韧带退行性变化所致腰腿疼痛等临床表现一系列疾病总称,多造成退变性腰椎管狭窄、腰椎滑脱等病变。LDDD病因较为复杂,且尚未明确其发病机制,因而临床未能取得理想疗效。近年来,诸多新技术如基因技术生物学,极大促进了LDDD的研究进展,该研究对其具体进展进行综合论述,以期为临床研究提供参考。

As a common spinal diseases,lumbar degenerative disk diease（LDDD） is defined by relevant scholars as the general name of a series of disease which have the clinical manifestation of waist and leg pain caused by degenerative changes of lumbar disc,articular process cartilages and surrounding ligament,and it always results in degenerative lumbar spinal stenosis and spondylolisthesis.Its clinical effect is not good because of complex causes and undefined pathogenesis.This paper reviews the progress of many new technologies such as gene technology and biology which greatly improve the research progress of LDDD in recent years so as to provide reference for clinical study.