果酸联合胶原蛋白敷料治疗颜面部痤疮临床疗效

Clinical effects of alpha hydroxy acid combined with collagen dressing in the treatment of facial acne

目的观察果酸联合胶原蛋白敷料治疗颜面部痤疮的效果。方法将66例痤疮患者,随机分为治疗组(果酸联合胶原蛋白敷料)和对照组(果酸治疗)。2组均果酸治疗,每2周1次,共4次;治疗组在果酸治疗后胶原蛋白敷料第1周每日1次,第2周隔日1次。结果治疗组和对照组总有效率分别为87.88%、51.52%,差异有统计学意义。结论果酸联合胶原蛋白敷料治疗颜面部痤疮安全有效,同时可改善表皮细胞微环境和促进皮肤组织新陈代谢,对皮肤干燥和细小皱纹等皮肤老化的修复有一定作用,从而提高患者生活质量,有临床推广价值。

Objective To investigate the efficacy of alpha hydroxy acid combined with collagen dressing in the treatment of facialacne. Methods Sixty-six patients with acne were randomly divided into treatment group （alpha hydroxy acid combined with collagen dressing） and control group（alpha hydroxy acid only）. Alpha hydroxy acid were applied to the patients for two months once every two weeks. Collagen dressing were treated afteralpha hydroxy acid on treatment group once a day during the first week and once every two days during the second week. Results The effective rates in the treatment group and the control group were 87.88% and 51.52% respectively, which had statistically significance between the two groups. Conclusion Alpha hydroxy acid combined with collagen dressingforfacial acne is safely and effectively, and has a certain effects on skin aging repair such as dry skin and fine wrinkle which can improve the life quality of patients. It has prospects of clinical distribution.