欣普贝生与催产素足月妊娠引产效果比较研究

Comparison of Effect Between Suppositories and Oxytocin for Labor Induction in Term Pregnancy

目的比较研究欣普贝生与催产素在足月妊娠促宫颈成熟及引产中的临床应用效果。方法选择在该院待产孕妇,随机将孕妇分为对照组和研究组。比较分析两组孕妇用药前后宫颈Bishop评分、引产效果、分娩方式以及新生儿情况等指标。结果与对照组孕妇相比,研究组孕妇用药后宫颈Bishop评分,引产成功率和总有效率,阴道顺娩率,新生儿出生后Apgar评分均明显提高,引产无效率和剖宫产率明显降低,两组比较差异均具有统计学意义(P<0.05)。结论欣普贝生能够促进足月妊娠宫颈成熟,提高引产成功率,降低剖宫产率,改善新生儿出生状态。

Objective To compare the clinical result between suppositories and oxytocin for cervical ripening and labor induction in term pregnancy.Methods The pregnant women in our hospital were selected and divided into control group and study group randomly.The Bishop scores before and after treatment,induction effects,mode of delivery and neonatal situation of the pregnant women in two groups were compared and analyzed.Results Compared with control group,the pregnant women in study group,the Bishop scores after treatment,the success rate of abortion and the total effective rate,delivery from spontaneous vaginal rate,the Apgar scores after birth of neonatal were increased significantly,while the inefficient rate of abortion and cesarean section rate was decreased significantly,the differences were significant statistically（P〈0.05）.Conclusion Dinoprostone could promote cervical ripening,improve the success rate of induction of labor,reduce the cesarean section rate and improve the state of neonatal for fullterm pregnancy.