异丙酚复合芬太尼或瑞芬太尼靶控静脉麻醉与静吸复合麻醉的比较

Target-controlled Intravenous Anesthesia Versus Intravenous Inhalational Anesthesia by Using Propofol-fentanyl or Propofol-remifentanil

目的对异丙酚复合芬太尼或瑞芬太尼靶控静脉麻醉与静吸复合麻醉的临床疗效进行分析。方法随机选取2012年4月—2014年4月90例来该院行腹腔镜胆囊切除术的患者,盲分法随机分为观察组与对照组各45例,对照组患者给予静脉复合麻醉方法 ,观察组患者采取靶控静脉麻醉,比较两组患者的麻醉效果。结果两组患者在麻醉诱导时SBP、DBP、HR及MAP无统计学意义(P>0.05),SBP<90 mmHg比重和插管反应率观察组患者要低于对照组(P<0.05),观察组患者的拔管时间以及术后康复时间(17±5.6、19±8.2)min均少于对照组(22±7.2、23±4.6)min,观察组在减少插管应激反应明显优于对照组(P<0.05)。结论在临床中应用异丙酚复合芬太尼或瑞芬太尼靶控静脉麻醉更加平稳,术后拔管以及恢复方面的临床应用价值更高,值得临床推广。

Objective To probe into the clinical effects of target-controlled intravenous anesthesia and intravenous inhalational anesthesia by using propofol-fentanyl or propofol-remifentanil.Methods 90 patients who received laparoscopic cholecystectomy from 2012 April to 2013 April were selected and randomly divided into the observation group and the control group,with 45 patients in each group.The control group was given intravenous inhalational anesthesia,and the observation group was given targetcontrolled intravenous anesthesia.The anesthetic effects of the two groups were compared.Results SBP,DBP,HR and MAP of the two groups during anesthesia induction were of no statistical difference（P〈0.05）.The SBP of the observation group was less than90 mmHg and its intubation response rate was significantly lower than that of the control group（P〈0.05）.The extubation time（17±5.6）min and postoperative recovery time（19±8.2）min of the observation group were significantly shorter than those（22±7.2、23±4.6）min of the control group.In reducing intubation stress reaction,the observation group was better than the control group（P〈0.05）.Conclusion Propofol-fentanyl or Propofol-remifentanil target-controlled intravenous anesthesia is more stable in the clinical application,and the clinical value of postoperative extubation and recovery is higher,so it is worth clinical promotion.