骨巨细胞瘤CT和MRI表现对照分析

Comparative Analysis of CT and MRI Findings of Giant Cell Tumor of Bone

目的通过对骨巨细胞瘤的CT和MRI表现对照分析,寻找CT和MRI表现之间的相关性及其与肿瘤复发的关系,进一步提高对骨巨细胞瘤CT和MRI表现的认识。方法搜集自1995年1月—2012年12月年期间在该院手术及病理证实为骨巨细胞瘤、随访2年以上并同时有CT和MR检查的195例病例资料,对照分析其CT骨皮质破坏中断情况、骨皮质膨胀程度、有无软组织肿块形成与MR病灶内实质成份比例、周围水肿程度等情况,并于肿瘤是否复发对照。结果 CT上骨皮质破坏程度与MRI上实质成份比例及病灶周围水肿程度差异有统计学意义(P<0.05)。CT及MRI表现与肿瘤是否复发对照显示,CT上骨质破坏程度与是否复发差异有统计学意义(P=0.018<0.05)。结论骨巨细胞瘤的CT表现与MRI表现有一定的内在联系,CT所示的骨质破坏程度与MRI中的实质成份比例、水肿程度等表现有关,提示肿瘤的侵袭性较高,并与肿瘤的复发具有一定相关性,但其病理学基础有待进一步研究。

Objective To find out the correlations between CT findings and MRI findings of giant cell tumor of bone and its relation with tumor recurrence by comparative analysis so as to further improve the understanding of the CT and MRI findings.Methods 195 patients with giant cell tumor of bone confirmed by operation and pathological examination who were followed-up for 2years and received CT and MRI scan were selected.CT showed cortical bone destruction,cortical bone expansion extent,with or without soft tissue mass,MR showed the proportion of lesions real ingredients,edema around the lesion were comparatively analyzed,and comparisons between them and tumor recurrence were done.Results There were statistically significant correlations between cortical bone destruction showed in CT and the proportion of lesions real ingredients,edema around the lesion showed in MRI（P〈0.05）.Comparison between CT and MRI features and tumor recurrence showed that there were statistically significant correlations the degree of bone destruction showed in CT and the rumor recurrence（P=0.0180.05）.Conclusion The CT and MRI findings of giant cell tumor of bone have some intrinsic correlation.The degree of bone destruction showed in CT is related to the real ingredients ratio,the degree of lesions peripheral edema showed in MRI,which indicates highly invasive of the tumor and shows some relation with tumor recurrence.But its pathological basis needs further study.