高压氧不同时机应用治疗重度颅脑外伤临床比较

Treatment of Severe Craniocerebral Trauma by Hyperbaric Oxygen at Different Timing

目的对高压氧不同时机应用治疗重度颅脑外伤进行比较。方法随机选取该院在2013年6月—2014年6月期间收治130例重度颅外伤患者,根据治疗时机分为对照组（n=65例）和实验组（n=65例）。对照组在伤后15~30 d给予高压氧治疗,实验组在伤后10~15 d给予高压氧治疗。治疗后,比较分析两组患者的治疗效果、GCS评分和苏醒时间。结果①实验组的治疗效果（治疗总有效率为87.67%）优于对照组（治疗总有效率为72.31%）,对比差异有统计学意义（P〈0.05）。②实验组的GCS评分（13.66±3.17）优于对照组（10.51±2.59）,实验组苏醒时间（23.8±2.7）短于对照组（31.6±4.5）,对比差异有统计学意义（P〈0.05）。结论尽早高压氧治疗重度颅脑外伤可以降低死亡率,提高治愈率,减少后遗症,缩短苏醒时间,具有重要意义。

Objective To compare the effect of hyperbaric oxygen at different timing in the treatment of severe craniocerebral trauma. Methods 130 patients with severe craniocerebral trauma admitted in our hospital from June 2013 to June 2014 were as-signed to （n = 65 patients） and the experimental group （n = 65 patients） according the timing of treatment. Patients in the control group were given hyperbaric oxygen therapy 15-30d after injury, while those in the experimental group were given hyperbaric oxy-gen therapy10-15d after injury. After treatment, the therapeutic effect, GCS score, and recovery time of the two groups were compared and analyzed. Results①experimental treatment group （total effective rate of 87.67%） than the control group （total ef-fective rate of 72.31%）, compared to a significant difference, with statistical significance, P〈0.05.② GCS score in the experimen-tal group （13.66 ±3.17） than the control group （10.51 ± 2.59）, the experimental group recovery time （23.8 ± 2.7） shorter than the control group （31.6±4.5）, contrast significantly different statistically significant, P 〈0.05. Conclusion The early hyperbaric oxygen treatment of severe craniocerebral trauma can reduce mortality and improve the cure rate and reduce complications, shorten recov-ery time, therefore it is of significance.