宫颈锥切对宫颈上皮内瘤样变的诊治

Diagnosis and Treatment of Cervical Intraepithelial Neoplasia by Conization of Cervix

目的探究宫颈锥切术对宫颈上皮内瘤样变(CIN)的诊断价值及治疗效果。方法回顾性分析2013年5月—2014年5月间在该院采用宫颈锥切术治疗的宫颈皮上瘤样变患者52例,使用常规的自身对照法,对比宫颈锥切术和阴道镜下宫颈多点活检的病理结果。对患者的临床资料进行回顾性分析。结果 52例患者全部采用Leep锥切,阴道镜活检为CINⅡ的30例患者中,与锥切病理结果相符的有26例,符合率为86.6%;阴道镜活检为CINⅢ的22例患者中,锥切术后18例与病理结果相符,符合率为81.8%。总体符合率为84.6%,差异无统计学意义(P>0.05)。病变级别均有所减轻。随访中,除了锥切后备确诊为宫颈癌的患者外,其他人并无复发现象。结论宫颈锥切术对宫颈上皮瘤样变有很好的诊断和治疗效果,术后需定期、严格的随访观察。

Objective To explore the diagnostic value and therapeutic effect of conization of cervix for cervical intraepithelial neoplasia. Methods 52 patients with cervical intraepithelial neoplasia who underwent conization of cervix in our hospital from May2013 to May 2014 were retrospectively analyzed. Pathologic findings of conization of cervix and that of colposcopic cervical multipoint biopsy were compared by self-control method. The clinical data of the patients was retrospectively analyzed. Results LEEP cone cutting surgery was performed for all the 52 patients. There were 30 patients in CINⅡaccording to colposcopic cervical multi-point biopsy, while 26 patients（out of the 30 patients） in the same class according to conization of cervix, and corresponding rate of the pathologic findings by the two different methods was 86.6%; There were 22 patients in CIN Ⅲ according to colposcopic cervical multi-point biopsy, while 18 patients（out of the 22 patients） in the same class according to conization of cervix, and cor-responding rate of the pathologic findings by the two different methods was 81.8%. The even corresponding rate was 84.6%, and there was no statistically significant difference（P 0.05）. Conclusion For cervical intraepithelial neoplasia, the diagnostic value and therapeutic effect of conization of cervix followed with strict and regular follow-up is significant.