解剖和非解剖型肝切除术用于肝细胞癌治疗临床研究

A Clinical Study of Anatomical and Non-anatomical Liver Resection for the Treatment of Hepatocellular Carcinoma

目的分析解剖型和非解剖型肝切除术对于治疗肝细胞癌的临床效果。方法将该院附属医院即将进行肝切除术的肝细胞癌患者150例随机分为解剖组和非解剖组,解剖组患者采用解剖型肝切除术,非解剖组采用非解剖肝切除术,对比两组相关指标数据。结果解剖组手术时间为(20.6±1.2)d,非解剖组为(21.6±0.8)d,解剖组与非解剖组术中出血量(m L)、术后并发症发生人数分别为:(732.8±88.6;8)、(1165.9±92.1;22)。通过对比结果进行分析,手术时间上两组比较差异无统计学意义(P>0.05),术中出血量和术后并发症的发生率解剖组要明显的低于非解剖组;对于患者1年后的复发情况来讲,解剖组患者中出现复发的数量要明显的少于非解剖组患者,差异有统计学意义(P<0.05)。结论通过该次对于本院附属医院肝细胞癌患者进行分析和比较,对于采取肝切除术进行治疗的患者采用解剖型肝切除术疗效较好,术中的安全性较高,预后复发率也较低,具有较强的可行性。

Objective To analyze the clinical results of anatomical and non-anatomical liver resection for the treatment of hepatocellular carcinoma. Methods 150 patients with hepatocellular carcinoma who would receive liver resection in our affiliated hospital were randomly divided into dissection group and non-dissection group. The patients in the dissection group were treated with anatomical liver resection, while those in the non-dissection group with non-anatomical liver resection. Relevant indicators of the two groups were compared. Results The operative time of dissection group and of the non-dissection group were（20.6 ±1.2）d and（21.6±0.8）d respectively, and the difference was not statistically significant（P〉0.05）; the intraoperative blood loss of dissection group and of the non-dissection group were（732.8 ± 88.6） and（1165.9 ± 92.1） respectively, while the number of postoperative complications of the two groups were 8 and 22 respectively, and the differences were statistically significant（P〈0.05）; in terms of postoperative recurrence within one year, the number was obviously less in the dissection group than in the non-dissection group,and the difference was statistically significant（P〈0.05）. Conclusion This study indicates that the clinical result of anatomical liver resection for the treatment of patients is better, which is of high safety, low recurrence rate and strong feasibility.