孕早期妇女弓形虫感染对妊娠结局的影响分析

Analysis of the Impact of Toxoplasma Infection in Early Pregnancy on the Pregnancy Outcome

目的分析孕早期妇女弓形虫感染对妊娠结局的影响。方法回顾性分析该院2014年2月—2015年2月收治的1960例孕妇,根据不同感染情况分为三组,研究A组(活动性感染)、研究B组(既往感染)、研究C组(急性感染),另选取同期120例健康孕妇作为对照组,比较各组妊娠结局情况。结果研究B组与对照组不良结局妊娠发生率比较差异无统计学意义(P>0.05),但研究A组与研究C组比对照组高差异有统计学意义(P<0.05)。结论弓形虫活动性感染与急性感染和孕早期妇女的妊娠结局密切相关,可将检测弓形虫Ig M抗体作为孕妇孕前的检查项目之一。

Objective To analyze the impact of Toxoplasma infection in early pregnancy on the pregnancy outcome. Methods The clinical data of 1960 pregnant women treated in our hospital between February 2014 and February 2015 were reviewed, and were divided into three groups according to the different infections, study group A （active infection）, study group B （ past infection）, and study group C （acute infection）. Another 120 normal pregnant women were selected as the control group. The pregnancy outcome of the four groups were compared. Results There was no significant difference registered in the incidence of adverse pregnancy out-come between study group B and the control group, （P〉0.05）. However, significant difference was shown in the adverse pregnancy outcome between the study group A and the control group, and between the study group C and the control group （P〈0.05）. Con-clusion Active Toxoplasma infection and acute Toxoplasma infection in early pregnancy are closely related with the pregnancy out-come, therefore the IgM antibodies to Toxoplasma gondii can serve as an indicator for pre-pregnancy physical examination.