心搏骤停后消化系统的损伤及低温治疗对消化系统影响的研究进展

Research Progress of the Influence of Digestive System Impairment After Cardiac Arrest and Therapeutic Hypothermia on Digestive System

目前,心搏骤停复苏患者自主循环恢复（ROSC）成功率逐渐提高,但患者最终的生存率仍然较低,心搏骤停后综合征（PCAS）或复苏后多脏器功能障碍综合征（MODS）为主要死亡原因。治疗性低温指将患者核心体温降至32~34℃,是目前唯一被证实能够提高心搏骤停患者生存率的方法。低温治疗在神经系统领域应用广泛并且成熟,但目前低温治疗对患者消化系统的受益情况仍存在争议。本文探讨了心搏骤停后消化系统损伤的病理生理机制,总结低温对胃肠道、肝脏及胰腺影响的相关研究,以期为心搏骤停后消化系统损伤的低温治疗提供借鉴。

At present,the success rate of return of spontaneous circulation（ ROSC） in patients with cardiac arrest has gradually improved,but the final survival rate of patients is still low. Post- cardiac arrest syndrome（ PCAS） and multiple organ dysfunction syndrome（ MODS） are the major causes of death. Therapeutic hypothermia is defined as patient＇ s core body temperature being down to 32 to 34 ℃,and it has been proven the only way to improve the survival rate of patients with cardiac arrest so far. Hypothermia has been widely used and has become mature in the field of nervous system,but the influence of hypothermia on the digestive system remains controversial. This paper discussed the pathophysiological mechanism of the digestive system injury following cardiac arrest,and made a review of the related research of the influence of hypothermia on gastrointestinal tract,liver and pancreas in order to provide references for hypothermia treatment after cardiac arrest.