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动脉瘤破裂蛛网膜下腔出血早期显微手术结合抗血管痉挛药物治疗的效果观察 被引量:3

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摘要 目的探讨动脉瘤破裂蛛网膜下腔出血早期显微手术结合抗血管痉挛药物治疗的临床疗效。方法选取2012-05—2014-04我院收治的动脉瘤破裂蛛网膜下腔出血患者48例,给予早期(3d内)显微手术夹闭动脉瘤,并结合术中术后抗痉挛药物治疗,总结分析患者的临床表现、影像学特点,按拉格拉斯哥预后评分(GOS)评价综合处理后的临床疗效。结果48例患者术中探查见蛛网膜下腔出血,破裂动脉瘤周围有血凝块合并脑血管痉挛,在分离瘤颈的过程中有8例动脉瘤破裂;术后脑血管造影显示,除1例床突旁动脉瘤有小部分残颈外,余47例动脉瘤均消失,原有脑血管痉挛症状减轻或消失,除2例术后发生脑血管痉挛外,余均未发生脑血管痉挛。治愈和好转共39例,好转率为81.25%;术后发生一过性偏瘫和原有偏瘫加重者共7例,出院时明显好转5例;出院时重度残疾2例,轻度残疾4例,死亡1例。结论早期手术可以有效防止颅内动脉瘤再次破裂出血,降低病死率;围手术期合理使用抗痉挛药物,对预防脑血管痉挛疗效显著。
出处 《中国实用神经疾病杂志》 2015年第22期21-23,共3页 Chinese Journal of Practical Nervous Diseases
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