血清尿酸和高敏C-反应蛋白在急性ST段抬高型心肌梗死中的变化

Changes of serum uric acid and high-sensitivity C-reactive protein with acute ST-segment elevation myocardial infarction

目的观察血清尿酸(SUA)、高敏C-反应蛋白(hs-CRP)浓度在急性ST段抬高型心肌梗死(STEMI)中的变化。方法选取2011年3月-2013年8月该院收治的STEMI患者50例作为观察组,50例门诊健康体检者作为对照组,采用尿酸酶法及免疫散射光比浊法分别测定2组患者的血清SUA及hs-CRP浓度。结果观察组患者血清SUA、hs-CRP水平均高于对照组,差异均有统计学意义(P<0.01)。结论高血清SUA、hs-CRP水平可能是导致STEMI的危险因素,可能与STEMI的发生有关。

Objective To explore the association between the serum uric acid（ SUA） and serum high-sensitivity C-reactive protein（ hs-CRP） and acute ST-segment elevation myocardial infarction（ STEMI）. Methods Selected STEMI patients50 cases from March 2011 to August 2013 in the hospital as observation group. Selected 50 cases of outpatient healthy subjects as control group. Measured the serum SUA of two groups using uric acid enzyme,Measured serum hs-CRP concentration using immune scattered light turbidity. Results The serum SUA and hs-CRP levels of patients in observation group were higher than control group,the difference was statistically significant（ P〈0. 01）. Conclusion Higher SUA and hs-CRP are possible the risk factors resulting in STEMI,and have the association with STEMI.