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小剂量罗哌卡因与布比卡因分别腰硬联合麻醉用于妊娠并高血压剖宫产对孕妇心血管反应的影响 被引量:11

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摘要 目的观察小剂量罗哌卡因与布比卡因分别腰硬联合麻醉对妊娠期合并高血压剖宫产患者心血管系统的影响。方法将206例妊娠合并高血压择期行剖宫产手术患者随机分为研究组和对照组各103例,研究组给予小剂量罗哌卡因腰硬联合麻醉,对照组注入小剂量布比卡因腰硬联合麻醉。观察2组患者的麻醉镇痛效果、心血管系统变化情况及不良反应发生情况。结果研究组0级最佳麻醉镇痛效果占比明显高于对照组,3级最差麻醉镇痛效果占比明显低于对照组,差异均有统计学意义(P<0.01)。麻醉后研究组患者的RPP、MVO2及对照组患者的SBP、MAP均低于麻醉前,对照组患者的HR明显高于麻醉前,且研究组患者的RPP和MVO2明显低于对照组,SBP、MAP却明显高于对照组,差异均有统计学意义(P<0.05)。2组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论对于妊娠并高血压剖宫产患者采用小剂量罗哌卡因腰硬联合麻醉,麻醉效果优于0.75%布比卡因,且对心血管系统的影响较小,具有较高的临床价值。
出处 《临床合理用药杂志》 2015年第34期108-109,共2页 Chinese Journal of Clinical Rational Drug Use
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