超声对幽门螺杆菌感染患儿与胃排空障碍的相关性研究

Study on the Relationship between Helicobacter Pylori and Gastric Emptying Function by Ultrasonic

目的本研究旨在通过应用超声技术通过对患儿胃排空功能的检测，探讨儿童幽门螺杆菌（helicobacterpylori，Hp）感染与胃排空障碍的关系。方法选取2011年8月～2014年7月于笔者医院儿科消化门诊诊断为Hp阳性功能性消化不良（FD）患者82例，随机分成Hp阳性组42例以及Hp治疗组40例。Hp阳性组给予吗丁啉治疗4周，而Hp治疗组则先进行彻底的Hp感染清除再服用吗丁啉，两组患儿在治疗前后均接受B型超声进行胃排空功能的检测。结果Hp治疗组餐后30min、60min和90min的胃窦液体排空率明显高于阳性组（t=2．879、7．432、10．443，P=0．039、0．012、0．004）；经过Hp感染治疗后对胃窦排空率治疗前后结果进行比较，治疗后的排空率明显高于治疗前（t=5．342、7．643、4．873，P=0．029、0．015、0．036）；治疗后Hp治疗组的胃半排空时间低于Hp阳性组（19．54±1．56VS25．45±3．25），差异具有统计学意义（t=7．867，P=0．034）；两组患儿治疗后结果均低于治疗前，差异有统计学差异（t=10．567、12．876，P=0．003、0．001）。结论儿童幽门螺杆菌感染与胃排空障碍具有重要关系，根除幽门螺杆菌感染可以有效提高儿童消化不良疾病的排空率，减少其出现营养不良的机会。

Objective To explore the relationship between helicobacter pyloriinfection and gastric emptying function by the applica- tion of three dimensional ultrasound technology to detect gastric emptying function. Methods A total of 82 patients diagnosed with posi- tive functional dyspepsia （FD） with helieobacter pylori（Hp） infection were randomly divided into Hp positive group （42 cases） and Hp treatment group （40 cases） between August 2011 and July 2014. The patients of the Hp positive group received Domperidone for 4 weeks, while Hp treatment were given Hp clearance before Domperidone treatment. All patients were given B type ultrasonic detection of gastric emptying function before and after treatment. Results The gastric liquid emptying at 30min, 60min and 90min after eating of Hp treat- ment group were significantly higher than those of Hp positive group （ t = 2. 879, 10. 443 ,P = 0. 039, 7. 432, 0. 012, 0. 004）. After Hp infection treatment, the gastric emptying rate results showed that the emptying rate was significantly higher than those after treatment （t = 5. 342, 7. 643, 4. 873, P = 0. 029, 0. 015, 0. 036）. The gastric half empting time of Hp treatment was less than that in Hp positive group [ （ 19.54 ± 1. 56 ） vs （25.45 ± 3.25 ） ], and the difference was statistically significant （ t = 7. 867, P = 0. 034 ）. The results after treatment were lower than those before in two groups and the difference was statistically different （t = 10. 567, 12. 876, P = 0. 003, 0. 001 ）. Conclusion The important relationship is located between children＇s helicobacter pylori infection and gastric emptying rate. Eradication kip infection can effectively improve the children＇s dyspepsia emptying rate and reduce the emergence of malnutrition opportunity.