期刊文献+

牙髓干细胞在组织工程领域的研究进展 被引量:5

Study progress of dental pulp stem cells in tissue engineering
下载PDF
导出
摘要 种子细胞的获得、培养与分化是组织工程的前提和基础,将干细胞作为种子细胞用于组织工程的构建受到越来越多学者的关注。牙髓干细胞(DPSCs)是存在于牙髓组织中的一种成体干细胞,是一种新兴的组织工程种子细胞,对于组织器官的再生具有重要的意义。本文就牙髓干细胞在组织工程的研究现状作一综述,并对其临床应用前景进行讨论。 In recent years, modern tissue engineering is becoming emerging and developing rapidly, and the acquisition, cultivation and differentiation of seed cells is the premise and foundation of the construction of tissue engineering, so more and more scholars pay attention to stem cells as seed cells for tissue engineering construction. Dental pulp stem cells(DPSCs) is a kind of adult stem cells derived from dental pulp, and as a new kind of seed cells of tissue engineering, the study of DPSCs presents important significance in tissue and organ regeneration. In this review, we introduced the progress of studies on dental pulp stem cells and discussed their clinical application prospects.
出处 《华西口腔医学杂志》 CAS CSCD 北大核心 2015年第6期656-659,共4页 West China Journal of Stomatology
关键词 牙髓干细胞 多向分化 组织工程 应用前景 dental pulp stem cells multiple differentiation tissue engineering application prospect
  • 相关文献

参考文献23

  • 1Collart-Dutilleul PY, Secret E, Panayotov I, et al. Adhesion and proliferation of human mesenchymal stem cells from dental pulp on porous silicon scaffolds[J]. ACS Appl Mater Interfaces, 2014, 6(3):1719-1728.
  • 2Gronthos S, Mankani M, Brahim J, et al. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo[J]. Proc Natl Acad Sci USA, 2000, 97(25): 13625-13630.
  • 3Tatullo M, Marrelli M, Shakesheff KM, et al. Dental pulp stem cells: function, isolation and applications in regenera- tive medicine[J]. J Tissue Eng Regen Med, 2014: doi: 10. 1002/terrn. 1899.
  • 4Yang M, Zhang H, Gangolli R. Advances of mesenchymal stem cells derived from bone marrow and dental tissue in craniofacial tissue engineering[J]. Curr Stem Cell Res Ther, 2014, 9(3):150-161.
  • 5Murphy MB, Blashki D, Buchanan RM, et al. Adult and umbilical cord blood-derived platelet-rich plasma for me- senchymal stem cell proliferation, chemotaxis, and cryo- preservation[J]. Biomaterials, 2012, 33(21):5308-5316.
  • 6Gottipamula S, Sharma A, Krishnamurthy S, et al. Human platelet lysate is an alternative to fetal bovine serum for large- scale expansion of bone marrow-derived mesenchymal stro- mal cells[J]. Biotechnol Lett, 2012, 34(7): 1367-1374.
  • 7Struys T, Moreels M, Martens W, et al. Ultrastructural and immunocytochemical analysis ofmultilineage differentiated human dental pulp- and umbilical cord-derived mesenchy- mal stem cells[J]. Cells Tissues Organs, 2011,193(6):366- 378.
  • 8Yang X, Walboomers XF, van den Beucken JJ, et al. Hard tissue formation of STRO-l-selected rat dental pulp stem cells in vivo[J]. Tissue Eng Part A, 2009, 15(2):367-375.
  • 9郭红延,吴补领,郭希民,王常勇.大鼠牙髓干细胞的培养和鉴定[J].牙体牙髓牙周病学杂志,2004,14(5):242-245. 被引量:15
  • 10Gronthos S, Brahim J, Li W, et al. Stem cell properties of human dental pulp stem cells[J]. J Dent Res, 2002, 81(8): 531-535.

二级参考文献14

  • 1Kettunen P,Karavanova I,Thesleff I.Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1,-2,-3,and of FGFR4; and stimulation of cell proliferation by FGF-2,-4,-8,and -9.Dev Genet. 1998;22(4)
  • 2Kitamura C,Kimura K,Nakayama T,et al.Temporal and spatial expression of c-jun and jun-B proto-oncogenes in pulp cells involved with reparative dentinogenesis after cavity preparation of rat molars[J].J Dent Res,1999,78(2):673
  • 3Nakashima M,Nagasawa H,Yamada Y,et al.Regulatory role of transforming growth factor-beta,bone morphogenetic protein-2,and protein-4 on gene expression of extracellular matrix proteins and differentiation of dental pulp cells[J].Dev Biol,1994,162(1):18
  • 4Gronthos S,Mankani M,Brahim J,et al.Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo[J] .Proc Natl Acad Sci USA,Vol. 97,Issue 25,13625-13630,December 5,2000
  • 5Shi S,Gronthos S,Chen S,et al.Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression[J].Nat Biotechnol,2002,20(6):587
  • 6Ruch JV.Odontoblast commitment and differentiation[J].Biochem Cell Biol,199,76(6):923
  • 7Butler WT.Dentinspecificproterns[J].Methods Enzymol,1987,145:290
  • 8Macdougall M,Gu TT,Luan X,et al. identification of a novel isoform of mouse dentin matrix protein1:spatial expression in mineralized tissues
  • 9Seale P,Rudnicki MA.A new look at the origin,function,and ""stem-cell"" status of muscle satellite cells[J].Dev Biol,2000,218:115
  • 10Thorgeirsson SS.Hepatic stem cells[J].Am J Pathol,1993,142:1331

共引文献14

同被引文献44

引证文献5

二级引证文献22

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部