韧带样型纤维瘤病的超声表现及病理特征研究

Ultrasonic manifestations and pathological features of desmoid-type fibromatosis

目的探讨韧带样型纤维瘤病(DF)的超声特征及病理特征。方法回顾分析38例经病理证实为DF的病例,分析其超声特征与病理表现。结果 38例DF中腹壁外型22例、腹壁型11例及腹内型5例。超声主要表现为沿肌纤维浸润性生长的低回声肿块,均未见坏死出血和囊性变灶;病理特征表现为无包膜,呈浸润性生长,来源于纤维母细胞和肌纤维母细胞,瘤细胞无明显异型性,无明显病理性核分裂象。结论超声对DF的诊断及鉴别诊断有一定帮助,但最终确诊仍需依靠病理检查。

Objective To explore the ultrasonic manifestations and pathological features of（desmoid-type fibromatosis,DF）. Methods We retrospectively investigated 38 DF were histologically and pathologically proven,and then the sonographic images about lesion location,size,echotexture and vascularity were investigated. Results Thirty-eight lesions were detected,of which 22 were located in extra-abdominal,11 were in abdominal wall muscles,5 were in intra-abdominal. Typical sonographic features of DF were spindle-or oval-shaped,hypo echoic texture,aggressively growing,none of them had cystic,hemorrhagic or necrosis change. The pathological features of DF includes：no tissue infiltration,no obvious capsule or boundary,tumor cell consist of fibroblasts and myofibroblasts,and rare in pathological mitotic figure. Conclusion Although ultrasonic manifestations is helpful for diagnosis and differential diagnosis of DF,pathological diagnosis is accurate.