卒中急性期患者抑郁的危险因素分析

Risk Factors Analysis of Post-stroked Depression

目的:研究卒中患者急性期发生抑郁的危险因素。方法:收集卒中患者357例,对发生抑郁的可能危险因素,年龄、性别、既往卒中史、抑郁病史、卒中的严重程度、残疾程度、认知障碍进行分析。结果:357例患者中,发生抑郁100例(28.01%,抑郁组),未发生抑郁257例(71.99%,无抑郁组)。抑郁组的美国国立卫生研究院卒中量表(NIHSS)评分、年龄、既往抑郁病史高于无抑郁组(P<0.05),Logistic分析提示,年龄、抑郁病史及NIHSS评分与抑郁相关(P<0.05)。结论:卒中后抑郁在急性期发生率高,应给予足够的重视及早期治疗。

Objective： To discuss the risk factors of depression in acute stroke patients. Methods： Three hundred and fifty-seven acute stroke patients were enrolled. The risk factors such as age, sexuality, previous stroke, former depression, stroke severity, disability and recognition deficit were analyzed. Results： Of all the patients, 100 cases （28.01%, depression group） were diagnosed of depression, 257 cases （71.99%, no-depression group） without de-pression. The NIHSS scores, age and proportion of previous depression in the depression group were higher than those of no-depression group （P〈0.05）. Logistic analysis indicated that age, history of depression and NIHSS scores were associated with depression （P〈0.05）. Conclusion： Depression is common in the acute stoke patients, emphasis and early treatment are essential.