介入溶栓术治疗急性闭塞性脑梗死临床分析

Clinical analysis of interventional thrombolysis in acute cerebral infarction

目的 探讨介入溶栓术治疗急性闭塞性脑梗死疾病的效果以及预后. 方法 选择2011年5月至2014年7月于濮阳市人民医院接受急性闭塞性脑梗死治疗的患者43例,对其实施介入溶栓治疗,回顾性分析其临床资料. 结果 43例患者中25例患者发病时间〈3 h,治疗有效23例,有效率为92%;18例患者发病时间为3-6 h,治疗有效11例,有效率为61.11%. 发病〈3 h患者的治疗有效率明显优于发病时间为3-6 h患者. 43例患者中颅内出血7例,其中2例死亡;4例脑出血患者中3例伴随高血压症状,1例伴随糖尿病,4例脑出血患者表现为脑水肿,对症治疗后好转;2例脑水肿症状严重,已形成脑疝,治疗好转后出现栓塞,治疗无效死亡. 结论 急性闭塞性脑梗死患者实施介入溶栓治疗方式,患者的发病时间越短,其治疗效果越好. 严格按照手术适应证实施可有效降低患者出现并发症的风险.

Objective To investigate the effect and prognosis of interventional thrombolysis in treatment of acute cerebral infarction .Methods Forty-three patients with acute occlusive infarction from May 2011 to July 2014 were selected , they all received interventional thrombolysis , the clinical data were retrospectively analyzed .Results Among the 43 patients, 25 patients had onset 〈3 h, and 23 cases with effective treatment , the effective rate was 92%;there were 18 patients onset time of 3 to 6 h, and 11 cases with effective treatment , the effective rate was 61.11%.The effective rate of onset 〈3 h treatment of pa-tients was better than the onset time of 3 to 6 h patients.Among the 43 patients, seven patients with in-tracranial hemorrhage , 2 cases died; Among the 4 cases of cerebral hemorrhage , 3 cases complicated with high blood pressure , 1 case complicated with diabetes , the clinical symptoms of the 4 cases were cerebral ede-ma, and they got better after symptomatic treatment .Two cases with severe symptoms of cerebral edema , had formed hernia, they died because of embolism after treatment .Conclusions For interventional thrombolysis in treatment of patients with acute cerebral occlusive , the incidence of patients is shorter , the effect is better . Accordance with the indications for surgery strictly can effectively reduce the risk of complications .