磷酸肌酸钠治疗新生儿缺氧缺血性心肌损害的效果观察

Efficacy of creatine phosphate sodium on neonatal hypoxic-ischemic myocardial injury

目的 探讨磷酸肌酸钠治疗新生儿缺氧缺血性心肌损害的临床疗效. 方法 对照组给予临床常规治疗,研究组在常规治疗基础上加用磷酸肌酸钠,记录两组缺氧缺血性心肌损害新生儿临床疗效及治疗前后实验室心肌酶谱检查结果变化情况,给予统计学分析后得出结论. 结果 研究组临床总有效率为90.48%,显著高于对照组（66.67%,P〈0.05）;两组各项实验室检验结果均较治疗前有所改善,且研究组改善效果更为理想,差异有统计学意义（P〈0.05）. 结论 对缺氧缺血性心肌损害新生儿在常规治疗基础上加用磷酸肌酸钠可显著提高治疗效果,有利于保障患儿的生活质量及生命安全.

Objective To investigate the clinical efficacy of creatine phosphate sodium on neonatal hypoxic -ische-mic myocardial injury .Methods The control group received routine clinical treatment ,the study group received creatine phosphate sodium on the basis of above conventional therapy ,the clinical efficacy and the change of myocardial enzymes be-fore and after treatment were recorded , and giving statistical analysis concluded .Results The total clinical efficiency rate of study group was 90.48%, which was significantly higher than that in the control group （ 66.67%, P〈0.05）.The re-sults of laboratory tests of the two groups improved after treatment compared with before treatment , and the study group im-proved better than that in the control group ,the difference was significant （ P〈0.05） .Conclusions Based on the conven-tional treatment , combined with creatine phosphate sodium in treatment of neonatal hypoxic-ischemic myocardial injury can significantly improve the therapeutic effect , it can help protecte the quality of life and the lives of children .