首发轻中度青年抑郁症患者接受认知行为治疗前后的内隐刻板印象

Implicit Stereotype before and after Cognitive Behavior Therapy in First- episode Young Patients with Mild- to- moderate Major Depressive Disorder

目的:探讨首发轻中度青年抑郁症患者接受认知行为治疗前后内隐刻板印象的变化。方法:选取首次发病未经治疗的青年抑郁症患者21例和正常对照者20例,抑郁症患者接受8次的认知行为治疗,正常被试仅接受8周的观察,实验前后,所有被试均接受汉密尔顿抑郁量表(Hamilton Depression Scale,HAMD-24)、自动思维问卷(The Automatic Thoughts Questionnaire,ATQ)、内隐联想测验(Implicit association test IAT)评估与测验。结果:1实验组治疗后,在HAMD总分、ATQ总分、IAT测验效应值均有显著性改善,分别为(t=-6.81,-3.06,3.86;P<0.05);2治疗后与正常对照组相比,实验组在HAMD总分、ATQ总分、IAT测验效应值均存在显著性的差异,分别为(t=3.50,3.81,-3.11;P<0.05)。结论:认知行为治疗对首发轻中度抑郁症患者内隐刻板印象的改善具有一定的积极意义。

Objective：To explore the effectiveness of cognitive behavior therapy for implicit stereotype of patients with mild-to-moderate major depressive disorder （ MDD） .Methods：21 First-episode mild-to-moderate patients with MDD and 20 matched healthy volunteers were recruited .The MDD group re-ceived cognitive behavior therapy for 8 weeks;The health control （ HC） group did not receive any medica-tion.Before and the after of experiment ,all the subjects accepted the Hamilton Depression Scale （ HAMD-24）,the Automatic Thoughts Questionnaire （ATQ）,implicit association test （IAT）,respectively.Re-sults：①After treatment,in the MDD group,the total scores of HAMD,ATQ,and the D_biep（D measure with built-in error penalty ） were enhanced significantly at the end of experiment than the start of experi-ment（t=-6.81,-3.06,3.86;P〈0.05））;②After treatment,compared with HC group,the MDD group was still higher in the total scores of HAMD,ATQ,D_biep（t=3.50,3.81,-3.11;P〈0.05）.Conclu-sion：Cognitive behavior therapy may be benefited for implicit stereotype of first -episode mild -to -moderate patients with MDD .