多发性大汗腺囊瘤合并大汗腺增生一例

Multiple apocrine hidrocystomas accompanied by apocrine hyperplasia：a case report

患者男，38岁。因左耳后丘疹、结节38年就诊。皮肤科检查：左耳后数十个大小不等肤色、淡红色丘疹、结节。组织病理示，真皮内一个不规则囊性结构，囊壁衬以2层上皮细胞，外层是扁平空泡的肌上皮细胞，内层为柱状或小的立方状细胞，胞质嗜酸性，可见顶浆分泌现象，囊壁周围包绕纤维样基质。真皮下部可见大量增生的大汗腺。结合临床资料及病理学改变，诊断为大汗腺囊瘤合并大汗腺增生。

A 38-year-old man complained of multiple papules and nodules in the left retroauricular region for 38 years. On physical examination, there were tens of irregularly sized, skin-colored or pink papules and nodules in the left retroauricular region. Pathological examination showed a large irregularly shaped unilocular cystic space surrounded by a fibrous pseudocapsule in the dermis. The cystic space was lined by a double layer of epithelial cells, including an outer layer of flattened vacuolated myoepithelial cells and an inner layer of cuboidal or columnar secretory cells with eosinophilic cytoplasm. Apocrine secretion was present. Numerous hyperplastic apocrine glands were seen in the deep dermis. A final diagnosis of multiple apocrine hidrocystomas accompanied by apocrine hyperplasia was rendered based on the clinical and pathological presentations.