摘要
目的综述神经调控血管生成机制的研究进展。方法广泛查阅近年国内外有关血管生成的神经调控机制文献,对神经和血管的相互联系及涉及的相关作用机制及其研究进展进行综述。结果神经调控血管生成过程有赖于神经血管单元中多种细胞间的相互协同作用及多种细胞因子的共同参与,还与神经再生、突触重塑等多种修复机制密切相关,具体作用机制有待进一步研究。结论神经调控血管生成机制的研究将有助于对血管神经损伤性疾病再生修复过程的认识。
Objective To review the research progress of neural regulation mechanism of vasculogenesis. Methods The relevant literature on neural regulation mechanism of vasculogenesis was extensively reviewed. Results Neural regulation ofvasculogenesis depends on synergistic effect among various ceils ofneurovascular unit, and co-participation of multiple cytokines, and it is closely related to a variety of repair mechanism, such as nerve regeneration and synaptic plasticity, but the specific mechanism need to be further investigated. Conclusion The research of the neural regulation mechanism ofvasculogenesis will contribute to further understanding repair mechanism of nerves and vessels injuries.
出处
《中国修复重建外科杂志》
CAS
CSCD
北大核心
2015年第12期1570-1573,共4页
Chinese Journal of Reparative and Reconstructive Surgery
基金
国家自然科学基金资助项目(30772299)~~
关键词
血管生成
神经调控
神经血管单元
神经干细胞
内皮祖细胞
Vasculogenesis
Neural regulation
Neurovascular unit
Neural stem cells
Endothelial progenitor cells
