乳腺癌及乳腺纤维瘤超声及造影特征的对比研究

The contrast study on the contrast- enhanced ultrasonography in the patients with mammary cancer and mammary fibroma

目的:探讨超声及造影特征对乳腺癌的临床诊断价值。方法:2013年1月1日至2014年12月31日在包头医学院第一附属医院住院的66例乳腺癌及85例乳腺纤维瘤患者,术前行常规超声及超声造影检查,观察肿块超声及造影特征,所有病例均经手术证实并与病理结果相对照。结果:66例乳腺癌患者与85例乳腺纤维瘤患者超声造影的开始增强时间、达峰时间、渡越时间、开始消退时间、完全消退时间相比较均有统计学意义(P<0.05);乳腺癌病灶测值明显大于造影前(P<0.05),可见穿支血管并呈快进慢出,病灶内造影剂分布不均匀,造影剂呈离心性增强,局部造影剂滞留;乳腺纤维瘤病灶测值与造影前相比较差异无统计学意义(P>0.05),可见环绕血管并呈慢进快出,病灶内造影剂分布均匀,造影剂呈向心性增强,无造影剂滞留。结论:超声及造影检查对乳腺癌和乳腺纤维瘤的鉴别诊断具有重要的指导价值。

Objective：To evaluate the clinical value of contrast-enhanced ultrasonography（ CEUS） in the diagnosis of mammary cancer. Methods：66 cases of mammary cancer and 85 cases of mammary fibroma from January 1st, 2013 to December 31st, 2014 in the First Affiliated Hospital of Baotou Medical College were selected to perform routine ultrasound examination and CEUS before the operation so as to observe the characteristics of breast masses. All the cases were confirmed by operation and compared with the results of pathology examination. Results：The 66 cases of mammary cancer were significantly dif-ferent from the 85 cases of mammary fibroma in the initiation time, peak time, transit time, fading time and disappearing time on CEUS （ P 〈0. 05）;In mammary cancer, the maximum diameter of the lesion was significantly larger than that before CEUS （ P 〈0. 05）;The perforator vessel could be seen, which the radiocontrast agent entered rapidly and came out of slowly;The radiocontrast agent in the lesion was heterogeneously distributed and enhanced cen-trifugally, with retention in some regions. As for mammary fibroma, the maximum diameter of the lesion was not significantly larger than that before CEUS （ P 〉0. 05）;The radiocontrast agent entered slowly and came slowly out of the perforator vessel;The radiocontrast agent in the lesion was homogeneously dis-tributed and enhanced centripetally, without signs of retention. Conclusions：CEUS has important instructional value to the diagnosis of mammary cancer and mammary fibroma clinically.