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番木瓜脂肪酶的应用进展

Application progress of carica papaya lipase
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摘要 介绍了番木瓜脂肪酶(CPL)的来源及应用。CPL作为一个与木瓜中的水不溶部分紧密结合的自固定化脂肪水解酶,应用前景非常广泛:能够催化脂肪酸和油酸;催化酸与醇的酯化,醇与酯的酯交换反应;催化2-芳基丙酸类药物的酶促拆分;及在其他方面的应用。 Carica papaya lipase（CPL） is attracting more and more interest. This hydrolase, being tightly bonded to the water-insoluble fraction of crude papain, is thus considered as a＂naturally immobilized＂biocatalyst.Several applications have already been described： Capable of catalyzing fatty acid and oleic acid; Catalyzed esterification of acids and alcohols, alcohol and ester exchange reaction; Catalyze enzymatic resolution 2-aryl-propionic acid drugs; Applications in other areas.
作者 谢龙 辛嘉英 王艳 孙立瑞
机构地区 哈尔滨商业大学食品科学与工程重点实验室 中国科学院兰州化学物理研究所羰基合成与选择氧化国家重点实验室
出处 《化学工程师》 CAS 2015年第11期41-44,47,共5页 Chemical Engineer
关键词 番木瓜脂肪酶 植物脂肪酶 生物催化 选择性 酯合成 carica papaya lipase plant lipases biocatalysis selectivity ester synthesis
分类号 Q556 [生物学—生物化学]
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参考文献29

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二级参考文献65

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化学工程师
2015年 第11期

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