脾切除术后凶险性感染致严重脓毒症1例报道

Report of a case of overwhelming post-splenectomy infection caused by severe sepsis

目的探讨以严重脓毒症为主要表现的脾切除术后凶险性感染(OPSI)的临床特点。方法报道分析1例OPSI致严重脓毒症患者的临床资料,探讨其临床特点。结果患者,男,35岁,脾切除术后2年,因头痛、呕吐就诊仁济南院急诊科,检查结果显示为严重脓毒症,诊断为OPSI。给予患者抗感染及对症支持治疗,1周后症状趋于稳定,预后良好。结论 OPSI的发病率低,但病死率高,临床医师须对该病充分认识,做到早诊断、早治疗,以免延误病情。

Objective To explore the clinical characteristics of overwhelming post-splenectomy infection（OPSI）with main manifestation of severe sepsis.Methods Clinical data of a patient with severe sepsis caused by OPSI was reported and analyzed and the clinical characteristics were investigated.Results A 35-year-old male patient who underwent splenectomy two years before was admitted by the Department of Emergency of Renji Hospital South Campus due to headache and emesis.Examination results showed severe sepsis and the patient was diagnosed with OPSI and underwent anti-infectious treatment and symptomatic supportive treatment.After one week,the symptoms tended to be stable and the prognosis was good.Conclusion The incidence of OPSI is low but the mortality is high.Clinicians should be fully aware of this disease,so as to make early diagnose and treatment and avoid delay.