上消化道出血发病因素及与中医时相的相关性研究

Research on Relations between Pathogenic Factors of Upper Gastrointestinal Bleeding and Traditional Chinese Medicine Time Rhythm

目的:探讨杭州地区上消化道出血(UGIB)发病因素与中医时相的相关性研究。方法:收集2010年1月—2013年6月消化内科316例UGIB住院病例,统计不同发病因素的分布及与中医时相因素的相关性。结果:溃疡炎症因素相关的UGIB发病具有季节性、节气性;血管性因素与肿瘤性因素相关的UGIB无明显季节性及节气性。溃疡炎症因素相关的UGIB昼夜发病有统计学差异,各时辰间发病亦有统计学差异,发病高峰在卯时;血管因素相关的UGIB昼夜以及各时辰间的发病无显著差异;肿瘤因素相关的UGIB昼夜发病无统计学差异,但各时辰间的发病有统计学差异,发病高峰在卯时和辰时。结论:UGIB不同病因所致UGIB的发病与中医时相的关系存在差异。

Objective： To study the relativity of upper gastrointestinal bleeding（ UGIB） with the traditional Chinese medicine time rhythm. Methods： We collected all UGIB cases of inpatients from January 2010 to June 2013 in the Department of Digestion and counted up the UGIB cases of each pathogenic factors and studied the relations between the pathogenic factors of UGIB and the traditional Chinese medicine time rhythm. Results： Ulcer inflammatory factors of UGIB cases had significant difference with seasonal and solar term but the vascular factors and tumor factors of UGIB were unconcerned. The morbidity of ulcer inflammatory factors on day and night had significant differences and was correlated with time significant differences. The peak incidence at the period of the day was from 5 a. m. to 7 a. m. The vascular factors of UGIB had no relations with circadian time. There was no statistical difference between the tumor factors of UGIB with day and night but there iwas significant difference on each hour and the peak incidence at the period of the day was from5 a. m. to 7 a. m and 7 a. m. to 9 a. m. Conclusions： Each of different risk factors of UGIB has different relations with traditional Chinese medicine time rhythm.