摘要
目的探讨低水平PEEP通气模式在改善肥胖患者围术期低氧血症中的应用效果。方法以我院2010年1月-2014年12月收治的80例肥胖围术期发生低氧血症手术患者为观察对象,随机分为对照组和实验组,对照组接受传统IPPV通气模式加大潮气量治疗,实验组接受低水平PEEP模式治疗,观察两组麻醉前（T_1）、气管插管后30 min（T_2）、插管后60 min（T_3）、气管拔管后30 min（T_4）、拔管后60 min（T_5）时各项指标。结果实验组患者不同时间点PaETCO_2、Ppeak、PaCO_2、A-aDO_2、PaO_2等气道峰压和血气参数指标均明显优于对照组,CVP、HR、MAP等血流动力学指标明显优于对照组（P〈0.05）。结论肥胖患者围术期接受低水平PEEP通气模式治疗,能显著降低其低氧血症发生率,控制各项临床观察指标,值得临床推广应用。
Objective To explore the application effect of low PEEP ventilation mode in improving obese patient perioperative hypoxemia. Methods 80 obese patient perioperative hypoxemia from January 2010 to December 2014 of our hospital were selected as study objective.Patients were randomly divided into control group and experimental group.Patients in control group were treated with traditional IPPV ventilation mode combined with large tidal volume.Patients in experimental group were treated with low PEEP ventilation mode.Index at pre-anesthesia（T_1）,30 min after endotracheal intubation（T_2）,60 min after endotracheal intubation（T_3）,30 min after tracheal extubation（T_4） and 60 min after tracheal extubation（T_5） were observed and analyzed. Results Peak inspiratory pressure and blood gas parameters liked PaETCO_2、Ppeak、PaCO_2、A-aDO_2、PaO_2 at different time in experimental group were better than control group.At the same time,hemodynamic index liked CVP,HR and MAP was also better than that of control group respectively（P〈0.05）. Conclusion Obese patient perioperative accept low PEEP ventilation therapy can obvious decrease the incidence rate of hypoxaemia and control the clinical observation indexes,so it is worth to popularize in clinic.
出处
《中国当代医药》
2015年第33期41-42,46,共3页
China Modern Medicine
基金
江西省上饶市科技指导计划(20151CZD12)
