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5-硝基-2,3-吲哚二酮的合成

Synthesis of 5- nitroisatin
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摘要 本文研究了5-硝基-2,3-吲哚二酮合成的工艺,以水合三氯乙醛等为原料,经胺的烷基化、环合、硝化反应得到产品,并且进行了初步的优化,总收率达到73.6%。该工艺成本低,条件温和,操作简单,适合工业化生产。 We study the synthesis of 5-nitroisatin. 5-nitroisatin was synthesized from trichloroacetaldehyde etc. ,through the alkylation of amine,Cyclization reaction and nitration,and an overall yield of 73. 6%. The process has low cost and sim-ple,simple operation,and suitable for industrialized production.
作者 潘海龙 黄生建
机构地区 上虞盛晖化工股份有限公司
出处 《江西化工》 2015年第5期88-90,共3页 Jiangxi Chemical Industry
关键词 三氯乙醛 5-硝基-2 3-吲哚二酮 合成 trichloroacetaldehyde 5-nitroisatin Synthesis
分类号 TQ463.5 [化学工程—制药化工]
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参考文献5

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二级参考文献19

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共引文献10

江西化工
2015年 第5期

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