眼内注射康柏西普治疗视网膜分支静脉阻塞继发黄斑水肿的临床观察被引量：12

The Effects and Safety of Intravitreous Injection of Conbercept for Macular Edema Secondary to Branch Retinal Vein Occlusion

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摘要目的观察玻璃体腔内注射康柏西普治疗视网膜分支静脉阻塞(branch retina vein occlusion,BRVO)继发黄斑水肿(macular edema,ME)的疗效.方法对接受玻璃体腔内注射康柏西普治疗视网膜分支静脉阻塞(BRVO)继发黄斑水肿(ME)20例(20眼)进行回顾性分析,观察治疗后2周、4周、6周患者的最佳矫正视力(BCVA)及光学相关断层扫描(OCT)检查黄斑中心凹视网膜厚度(CMT)的变化.结果治疗后2周、4周、6周患者的最佳矫正视力(best-corrected visual acuity,BCVA)均有不同程度提高,光学相关断层扫描(OCT)显示黄斑中心凹视网膜厚度(central macular thickness,CMT)明显变薄,与治疗前相比有统计学意义(P<0.05).结论玻璃体腔内注射康柏西普治疗视网膜分支静脉阻塞继发黄斑水肿安全有效. Objective To investigate the effects and safety of intravitreous injection of Conbercept for macular edema secondary to branch retinal vein occlusion.Methods 20 eyes of BRVO with ME were enrolled in this study.All the patients were received loading doses 0.05 m L of injection with Conbercept.During the 2 months of followup, observations were made on changes of best corrected visual acuity（BCVA） and central macular thickness（CMT） by OCT.Results The differences of BCVA and CMT were statistically significant before and after the treatment at 2 weeks, 4 weeks and 6 weeks.Conclusion In the treatment of BRVO with ME,intravitreous injection of Conbercept can improve the visual function and relieve ME.

作者杨林红皇甫昌涛朱琳唐香李慧刘艳杨瑛

机构地区曲靖市第二人民医院眼科

出处《昆明医科大学学报》 CAS 2015年第11期147-149,共3页 Journal of Kunming Medical University

关键词视网膜分支静脉阻塞黄斑水肿康柏西普 Branch retinal vein occlusion Macular edema Conbercept

分类号 R774 [医药卫生—眼科]

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