益生菌制剂治疗130例抗生素诱发新生儿腹泻临床观察

Clinical analysis of probiotic cure on 130 neonatal children antibiotic associated diarrhea

目的:观察在应用抗生素的同时加用益生菌制剂防止对抗生素诱发的肠道菌群失调性腹泻的影响。方法:选取130例本科室因新生儿呼吸道、肺部、脐带感染住院的患者作为研究对象。65例作为治疗组,65例作为对照组,治疗组在常规治疗的基础上,口服三联双歧杆菌胶囊。比较两组腹泻治愈时间及治愈率。结果:治疗组腹泻治愈率高于对照组,差异有统计学意义(P<0.05)。结论:益生菌制剂可降低腹泻发生率。

Objective： To investigate the clinical analysis of probiotie preparation cure on neonatal children antibiotic associated diarrhea. Method： 130 antibiotic associated diarrhea neonatal children were divided into two groups of microecologie cure group and conventional cure group, 65 children in each group. Bifid-triple viable capsule were given to microecologic cure group compare with conventional cure group. The time and rate of recovery were compared. Result： The time and rate of recovery in conventional cure group were significantly higher than those in microecologie cure group. Conclusion： Probiotic preparation cure reduced antibiotic associated diarrhea of neonatal children.