2012~2014年我院质子泵抑制剂的应用分析

Analysis of proton pump inhibitors application in our Hospital During 2012-2014

目的：了解我院质子泵抑制剂（PPI）使用情况,为临床合理用药提供参考。方法：对我院2012~2014年质子泵抑制剂（PPI）的应用金额、用量、用药频度、限定日费用（DDC）等进行统计、分析。结果：2012~2014年我院PPI的总销售金额呈逐年增长趋势,销售金额排序居前3位的药品分别为泮托拉唑、奥美拉唑、兰索拉唑。我院注射用质子泵抑制剂的销售金额远远大于口服制剂。结论：PPI在我院临床使用广泛,应用基本合理,但仍存在无适应症使用、盲目预防性应用等不合理现象,建议医院制定质子泵抑制剂合理应用指南,临床用药严格把握用药指征,避免过度使用。

Objective：To probe into the use of proton pump inhibitors in our hospital for references of clinical rational use of drug. Methods：The utilization of Proton Pump inhibitors of our hospital during 2012-2014 was analyzed statistically in respect of the consumption sum, consumption amount , DDDs and DDC etc. Results ：The total consumption sum of PPI in our hospital increased year by year.Pantoprazole, Omepmzole,and Lansoprazole ranked among the top three in respect of consumption sum during 2012-2014. The consumption sum of the proton pump inhibitors for injection was significantly higher than that of the oral proton pump inhibitors. Conclusion ： There is widespread clinical use of PPI in our hospital, The use of PPI was reasonable on the whole, however, the phenomena such as noneindication drug use,blindly prophylactic use etc can still be seen.It is recommended that guidelines for rational use of proton pump inhibitors be established in hospital and mediation indications should be followed strictly in clinical use to avoid excessive use of proton pump inhibitors.