盐酸氨溴索治疗老年肺炎的疗效观察

Curative effect observation of ambroxol hydrochloride in the treatment of senile pneumonia

目的评价盐酸氨溴索注射液辅助治疗老年肺炎的疗效及安全性。方法 42例老年肺炎住院患者,随机分成观察组与对照组,各21例。对照组给予吸氧、抗感染等常规治疗,观察组在此基础上加用盐酸氨溴索辅助治疗。比较两组疗效。结果治疗后,观察组与对照组总有效率分别为85.71%和42.86%,差异有统计学意义(P<0.05)。观察组临床症状改善起效时间(40.25±6.28)h短于对照组(56.58±9.98)h,差异有统计学意义(P<0.05)。结论盐酸氨溴索治疗老年肺炎祛痰效果疗效显著,临床症状改善快,是一种安全、经济、有效的药物。

Objective To evaluate curative effect and safety by ambroxol hydrochloride injection in assistant treatment of senile pneumonia. Methods A total of 42 senile pneumonia patients were randomly divided into observation group and control group, with 21 cases in each group. The control group received conventional treatment by oxygen inhalation and anti-infection. The observation group received additional ambroxol hydrochloride for assistant treatment. Curative effects of the two groups were compared. Results After treatment, the observation group and the control group respectively had total effective rate as 85.71% and 42.86%, and their difference had statistical significance （P〈O.05）. The observation group had shorter improved clinical symptom onset time as （40.25 ± 6.28）h than （56.58 ± 9.98）h of the control group. Their difference had statistical significance （P〈0.05）. Conclusion Ambroxol hydrochloride provides precisely expectorant effect in treating senile pneumonia, with quick improvement in clinical symptom. It is a safe, economical and effective drug.