摘要
目的:优选通塞益脑口服液的水提醇沉工艺条件。方法:采用高效液相色谱(HPLC)法检测指标成分阿魏酸.通过正交试验考察水提过程中加水量、煎煮时间、煎煮次数对药材中阿魏酸含量的影响;以有效成分转移率和药液澄明度为指标,采用单因素实验考查醇沉工艺的最佳乙醇浓度,根据实验结果确定最佳的提取工艺。结论:该优选工艺重现性好,阿魏酸提取率高,达到了工艺优化的目的。
Purpose:Preferred Tongsai Yinao oral Liquid water extraction and alcohol precipitation conditions. Methods:HPLC detection index method ferulic acid, By orthogonal test water extraction process, add water, boiling time, boiling times on herbs ferulic acid content: Transfer rate of the active ingredient and liquid clarity of indicators, the use of single-factor experiments to examine the best alcohol concentration of ethanol precipitation process. Results: The preferred process reproducible, and ferulic acid extraction rate, reaching the purpose of process optimization.