奥曲肽联合普萘洛尔在肝硬化上消化道出血患者中的应用

Efficacy of Octreotide Combined With Propranolol in the Treatment of Patients With Upper Digestive Tract Bleeding Caused by Liver Cirrhosis

目的探讨奥曲肽联合普萘洛尔治疗肝硬化上消化道出血的临床效果。方法将84例肝硬化伴上消化道出血患者随机分为观察组和对照组,给予观察组奥曲肽联合普萘洛尔治疗,对照组奥曲肽治疗,比较两组患者止血时间、不良反应发生率及治疗效果。结果观察组平均止血时间为(49.38±4.87)min,比对照组(72.47±4.39)min短,在治疗效果及不良反应发生率方面,观察组均优于对照组,比较差异具有统计学意义(P<0.05)。结论奥曲肽联合普萘洛尔治疗肝硬化并发上消化道出血患者治疗效果显著,不良反应少。

Objective To investigate the clinical effect of octreotide combined with propranolol in the treatment of upper digestive tract bleeding caused by liver cirrhosis. Methods 84 cases of upper digestive tract bleeding caused by liver cirrhosis were randomly divided into the observation group and the control group,given to the observation group octreotide combined with propranolol in the treatment,control group of octreotide in the treatment,and adverse reactions,stop bleeding time occurrence rate and treatment effectwere compared between the two groups of patients. Results The average bleeding time in the observation group was（49.38±4.87）min, which was shorter than the control group（72.47±4.39）,and the observation group was superior to the control group,the difference was statistically significant（P〈0.05）. Conclusion Octreotide combined with propranolol in the treatment of liver cirrhosis complicated with upper digestive tract bleeding in patients with obvious curative effect,less adverse reactions.