包头市采暖期PM_(10)中有机提取物的致突变性研究

Mutagenicity of Organic Extracts from PM_(10) during Heating Period in Baotou

目的通过对包头市采暖期大气可吸入颗粒物(PM10)中有机提取物的致突变性研究,探讨包头市大气污染的危害程度。方法于采暖期分别采集包西机务段、王府井商厦、居然苑小区、包头医学院4个功能区的PM10样品,采用Ames试验对各个功能区PM10中的有机提取物进行致突变性研究。结果 4个功能区PM10中有机提取物均存在不同程度的致突变活性,且具有较好的剂量—反应关系,其中包西机务段、王府井商厦两点致突变性较强,居然苑小区和包头医学院较弱。结论包头市采暖期PM10中有机提取物成分中存在具有致突变活性的物质,提示本市大气可吸入颗粒物可能具有潜在的致癌危险性。

Objectives To investigate the mutagenicity of organic extracts from PM10 during heating period in Baotou. Methods PM10 samples were collected from 4 sampling points,including Baotou west locomotives,Wangfujing department store,Juranyuan district and Baotou medical college,during heating period; the mutagenicity of organic extracts from PM10 was investigated by Ames test. Results The mutagenicity of organic extracts from PM10 was different in these four sampling points and was in a good dose- response relationship; which was stronger in Baotou west locomotives and Wangfujing department store than in Juranyuan district and Baotou medical college.Conclusion The mutagenicity of organic extracts from PM10 suggested that there was a potential carcinogenicity of polluted atmospheric particulate matter in Baotou during heating period.