196例全血细胞减少症患者的骨髓象与临床病因分析

Analysis of myelogram and clinical pathogenesis of 196 cases of patients with pancytopenia syndrom

目的探讨全血细胞减少症的临床病因,提高诊断的准确率。方法对196例全血细胞减少症患者的骨髓象及临床资料进行回顾性分析。结果 196例全血细胞减少症的病因以血液系统疾病为主,占68.9%,主要为急性白血病(14.8%)、骨髓增生异常综合征(12.2%)、再生障碍性贫血(11.2%)、免疫相关性全血细胞减少症(10.2%);非血液系统疾病占31.1%,主要为结缔组织疾病(10.7%)、慢性肝病(7.2%)、感染(6.2%)。结论全血细胞减少症的病因复杂,需要密切联系临床进行综合分析,以明确病因,减少误诊和漏诊,提高其诊断的正确率。

Objective To explore the etiological spectrum of pancytopenia,in order to improve the diagnostic accuracy.Methods Retrospectively analysed myelogram and clinical data of 196 cases of patients with pancytopenia syndrom.Results The dominant cause of pancytopenia syndrom in 196 cases of patients was hematological diseases（accounted for 68.9%）,including acute leukemia（14.8%）,myelodysplastic syndrome（12.2%）,aplastic anemia（11.2%）and immune-related pancytopenia（10.2%）;while non-hematologic diseases accounted for 31.1%,including connective tissue diseases（10.7%）,chronic liver disease（7.2%）and infection（6.2%）.Conclusion Etiology of pancytopenia syndrom is complex,which should be comprehensively analysed with closely contacting clinics,in order to clarify the cause,reduce misdiagnosis and missed diagnosis and improve the diagnostic accuracy.