男性不育症精液微量元素与精子密度及精子活动力的关系

The relationship between trace elements and sperm density and motility in male infertility

目的探讨男性不育症患者精液中微量元素与精子密度和精子活动力的关系。方法选取2013年9月至2014年9月该院收治的男性不育症患者116例,分为精子密度异常组(59例)和精子活动力异常组(57例),另选取56例已育健康男性设为对照组,进行常规精液分析,同时测定精浆中微量元素钙、磷、镁、铜、铁和锌水平。结果精子密度异常组中钙、磷、锌和铁水平均低于对照组,铜水平高于对照组,差异均有统计学意义(P<0.05);精子活动力异常组中铜水平高于对照组,锌和铁水平低于对照组,差异均有统计学意义(P<0.05)。结论男性不育症患者精液中微量元素水平与精子密度和活动力密切相关,测定精液中微量元素对评估和治疗男性不育有一定临床意义。

Objective To investigate the relationship between semen trace elements and sperm density and motility in male infertile patients.Methods A total of 116 cases of male infertility patients recruited in this hospital from September 2013 to September 2014 were collected and divided into the sperm density anomaly group（59 cases）and sperm motility anomaly group（57 cases）.Other 56 cases of fertile healthy men were enrolled into the control group.Sperm density and motility were analyzed and levels of calcium,phosphorus,magnesium,copper,icon and zinc were detected in seminal plasma.Results Seminal level of calcium,phosphorus,zinc and iron in sperm density anomaly group were significantly lower than those in the control group,while the level of copper was higher than that in the control group,had statistically significant differences（P〈0.05）.Seminal level of copper in sperm motility anomaly group was higher than that in the control group,while levels of zinc and iron were lower than those in the control group,had statistically significant differences（P〈0.05）.Conclusion Sperm motility and density are significantly correlated with trace elements levels in seminal plasma.Routine determination of trace elements in seminal plasma in infertile men should be recommended,which could be helpful in fertility assessment and treatment.