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Metagenome-wide Association Studies Potentiate Precision Medicine for Rheumatoid Arthritis

Metagenome-wide Association Studies Potentiate Precision Medicine for Rheumatoid Arthritis
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摘要 An article recently published in Nature Medicine by the group led by Drs. Jun Wang and Yingrui Li from BGI-Shenzhen and Xuan Zhang from Beijing Union Medical College Hospital, Chinese Academy of Medical Sciences revealed the relationship between the human microbiome and rheumatoid arthritis (RA) [1]. Zhang et al. performed metagenomic shotgun sequencing and a metagenome-wide association study (MGWAS) on fecal, dental, and salivary samples from a large cohort of treatment-naYve RA individuals and healthy con- trols. As a result, they found that the gut microbiome and the oral microbiome exhibited significant differences between RA natients and normal subiects. More importantly, An article recently published in Nature Medicine by the group led by Drs. Jun Wang and Yingrui Li from BGI-Shenzhen and Xuan Zhang from Beijing Union Medical College Hospital, Chinese Academy of Medical Sciences revealed the relationship between the human microbiome and rheumatoid arthritis (RA) [1]. Zhang et al. performed metagenomic shotgun sequencing and a metagenome-wide association study (MGWAS) on fecal, dental, and salivary samples from a large cohort of treatment-naYve RA individuals and healthy con- trols. As a result, they found that the gut microbiome and the oral microbiome exhibited significant differences between RA natients and normal subiects. More importantly,
作者 Yigang Tong
出处 《Genomics, Proteomics & Bioinformatics》 SCIE CAS CSCD 2015年第4期208-209,共2页 基因组蛋白质组与生物信息学报(英文版)
关键词 ORAL RA
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