期刊文献+

Fetal alcohol spectrum disorder: molecular insights into neural damage reduction 被引量:1

Fetal alcohol spectrum disorder: molecular insights into neural damage reduction
下载PDF
导出
摘要 Fetal alcohol spectrum disorders(FASD)is a group of entirely preventable,lifelong conditions,which occur upon maternal alcohol use during pregnancy.This can result in severe consequences for the newborn and ultimately the family.It is usually characterized by delays in development and motor function,craniofacial abnormalities,and difficulties with learning,memory,speech,and academic achievement.According to the German guidelines for fetal alcohol syndrome (FAS) diagnosis, the prevalence of FASD ranges between 0.02-0.8% of all annual births and often the disorder is not recognized (Landgraf et al., 2013). The U.S. National Institutes of Health regard FAS as the most common nonhereditary cause of mental retardation. Thus, preventing programs, like the one undertaken by the Aus- tralian Government, which appointed a National FASD Techni- cal Network (Elliott, 2015), may seem a very reasonable strategy. Fetal alcohol spectrum disorders(FASD)is a group of entirely preventable,lifelong conditions,which occur upon maternal alcohol use during pregnancy.This can result in severe consequences for the newborn and ultimately the family.It is usually characterized by delays in development and motor function,craniofacial abnormalities,and difficulties with learning,memory,speech,and academic achievement.According to the German guidelines for fetal alcohol syndrome (FAS) diagnosis, the prevalence of FASD ranges between 0.02-0.8% of all annual births and often the disorder is not recognized (Landgraf et al., 2013). The U.S. National Institutes of Health regard FAS as the most common nonhereditary cause of mental retardation. Thus, preventing programs, like the one undertaken by the Aus- tralian Government, which appointed a National FASD Techni- cal Network (Elliott, 2015), may seem a very reasonable strategy.
作者 Diana Le Duc
出处 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第11期1764-1766,共3页 中国神经再生研究(英文版)
  • 相关文献

参考文献12

  • 1Bosco C, Diaz E (2012) Placental hypoxia and foetal development versus alcohol exposure in pregnancy. Alcohol Alcohol 47:109-117.
  • 2Dobbing J, Sands J (1979) Comparative aspects of the brain growth spurt. Early Hum Dev 3:79-83.
  • 3Elliott EJ (2015) Fetal alcohol spectrum disorders in Australia—the future is prevention. Public Health Res Pract 25:e2521516.
  • 4Epstein EE, Kahler CW, McCrady BS, Lewis KD, Lewis S (1995) An empirical classification of drinking patterns among alcoholics: binge, episodic, sporadic, and steady. Addict Behav 20:23-41.
  • 5Joshi S, Guleria RS, Pan J, Bayless K), Davis GE, Dipette D, Singh US(2006) Ethanol impairs Rho GTPase signaling and differentiation of cerebellar granule neurons in a rodent model of fetal alcohol syndrome. Cell Mol Life Sci 63:2859-2870.
  • 6Landgraf MN, Nothacker M, Heinen F (2013) Diagnosis of fetal alcohol syndrome (FAS): German guideline version 2013. Eur J Paediatr Neurol 17:437-446.
  • 7Le Due D, Spataru A, Ceanga M, Zagrean L, Schoneberg T, Toescu EC, Zagrean AM (2015) Developmental exposure to ethanol increases the neuronal vulnerability to oxygen-glucose deprivation in cerebellar granule cell cultures. Brain Res 1614:1-13.
  • 8Lu X, Li Y, Wang W, Chen S, Liu T, Jia D, Quan X, Sun D, Chang AK, Gao B (2014) 3 beta-hydroxysteroid-Delta 24 reductase (DHCR24) protects neuronal cells from apoptotic cell death induced by endoplasmic reticulum (ER) stress. PLoS One 9:e86753.
  • 9Pantazis NJ, Dohrman DP, Goodlett CR, Cook RT, West JR (1993) Vulnerability of cerebellar granule cells to alcohol-induced cell death diminishes with time in culture. Alcohol Clin Exp Res 17:1014-1021.
  • 10Singer D (1999) Neonatal tolerance to hypoxia: a comparative-physiological approach. Comp Biochem Physiol A Mol Integr Physiol 123:221-234.

同被引文献4

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部