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原发于骨上皮样血管内皮瘤的影像对比分析 被引量:1

Radiologic Signs Comparative Analysis of Osseous Epithelioid Hemangioendothelioma
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摘要 目的:提高对骨上皮样血管内皮瘤(EHE)的认识和影像诊断水平。方法:回顾性分析经手术病理证实的6例骨上皮样血管内皮瘤的X线平片、CT、MR和临床病理,结合文献对比分析各检查方法的影像特征。结果:3个病例表现为多发病灶,分别位于股骨下段、胫腓骨及足部;2个病例病灶位于胫骨下段;1例病灶位于股骨近端。X线平片及CT平扫示多灶性溶骨性骨破坏、硬化边,部分病灶内见"栅栏样"骨嵴,MR上病灶呈稍长T1、长T2信号,增强后呈明显强化。免疫组化提示肿瘤细胞表达血管内皮细胞标记如CD3l、CD34、Vimentin、CK呈阳性。结论:骨上皮样血管内皮瘤有一定的影像学特征,X线平片、CT和MR检查能为临床诊断及鉴别诊断提供有价值的信息。 Objective: To improve knowledge and imaging diagnosis of bone epithelioid hemangioendothelioma (EHE). Methods: We retrospectively analyzed X-ray, CT, MR and pathological data of six cases of bone epithelioid hemangioendothelioma which confirmed by operation and pathology, and summarize its imaging features. Results: Three patients' lesions, characterized by multiple osteolytic destruction, were located in distal femur, tibia, fibula and foot. Two cases of lesions were located in the lower tibia. One case of lesion was located in the proximal femur. The imaging features of X-ray and CT of these lesions were multifocal osteolytic bone destruction, hardening of the edge and there were fence -like lesions bone crests in part of the lesions. MR image features of these lesions were slightly long T1WI and long T2W1, and they had significant enhancement after contrast-enhanced scanning. Immunohistochemical studies showed that tumor cells CD31, Vimentin, CK(+), CD69 (Spotty +), CD163 (spot), FLI-1 (+), Ki67 (+ 〈 10%). Conclusion: EHE have some imaging characteristics. CT and MR imaging can provide valuable information for clinical diagnosis and differential diagnosis.
出处 《CT理论与应用研究(中英文)》 2015年第5期717-724,共8页 Computerized Tomography Theory and Applications
关键词 骨上皮样血管内皮瘤 X线 体层摄影技术 磁共振成像 免疫组化 Epithelioid hemangioendothelioma of bone X-ray Computer tomography Magnetic resonanceimaging Immunohistochemistry
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  • 1Tsuneyoshi M, Dorfman HD, Bauer TW. Epithelioid hemangioendothelioma of bone a clinicopathologic, ultrastructural, and imunohistochemical study[J]. AmericanJournal of Surgical Pathology, 1986, 10(11): 754一756.
  • 2Kleer CG, Unni KK, Mcleod RA. Epithelioid hemangioendothelioma of boneD]. AmericanJournal of Surgical Pathology, 1996, 20(11): 1301一1311.
  • 3血管恶性肿瘤:血管肉瘤、血管内皮瘤、血管外皮瘤[J].中国口腔颌面外科杂志,2008,6(4):269-269. 被引量:14
  • 4Ti llman RM, Choong PF, BeaboutJW, et al. Epithelioid hemangioendothlioma of bone[J]. Orthopedics, 1997, 20: 177-180.
  • 50' ConnellJX, Nielsen GP, Rosenberg AE. Epithelioid vascular tumors of bone: A review and Proposal of classification scheme[J]. Advances in Anatomic Pathology, 2001, 8(2): 74-82.
  • 6Chireac LR, Rice DC, Raymond AK. Epithelioid hemangioendothelioma in a patient with unusual in volvement of the rib and intercostal lymph nodes[J].Journal of Thoracic and Cardiovascular Surgery, 2006, 132(6): 1488-1489.
  • 7Gill R, 0' Donnell RJ, Horvai A. Utility of immunohistochemistry for endothelial markers in distinguishing epith巳iloid hemangioendothlioma from carcinoma metastatic to bone[J]. Archives of Pathology & Laboratory Medicine, 2009, 133(6): 967-972.
  • 8HartJ, Mandavilli S. Epithelioid angiosarcoma: A brief diagnostic review and differential diagnosis[J]. Archives of Pathology & Laboratory Medicine, 2011, 135(2): 268-272.
  • 9Evans HL, Raymond AK, Ayala AG. Vascular tumor of bone: A study of bone of 17 cases other than ordinary hemangioma, with an evaluation of the relationship of hemangioendothelioma of bone to epi thel ioid hemangioma, epithelioid hemangioendothelioma, and high-grade angiosarcoma[J]. Human Pathology, 2003, 34(7): 680-689.
  • 10Hermann G, Klein MJ, Abdelwahab IF, et al. Unifocal epithelioid hemangioendothelioma of the tibia: Case report[J]. Canadian Association of RadiologistsJournal, 2000, 51(5): 296一299.

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