生肌象皮膏药物组成变化及制剂研究进展

Research Progress of Content Composition Change and Preparation of Shengji Xiangpi Gaoyao

生肌象皮膏是传统的生肌收口外用药,其组成经历了上千年的变化,演绎成了现在市售的橡皮生肌膏组方。生肌象皮膏中的有效成分被疮面吸收后促使疮面"脓"的产生,同时疮面产生的"脓"又促使更多药物有效成分的释放和吸收。研究脓的变化对于揭示生肌象皮膏"生肌"作用的具体机制,具有重要的科学意义和经济价值。然而目前有些问题仍需深入研究,比如,象皮作为稀有资源,如何在各种动物皮中选择功效、成分类似于象皮的药物替代象皮;生肌象皮膏能调控多种生长因子的表达是否具有时序性和作用协同性等。

ShengjiXiangpiGaoyao is one of the traditional convergent for external use. The production of its constituent has experienced thousands of years of changes, as now commercially available ShengjiXiangpiGaoyao. As the production of active ingredients of skin cream after being absorbed by wound, at the same time of wound ＂ pus＂ prompted more drug release and absorption of active ingredi- ents. Changes on the pus can reveal the specific mechanism of the role of ＂production＂ and has important scientific significance and e- conomic value. However, some problems still need further research, such as, Xiangpi as a rare resource, how to choose efficacy in a vari- ety of animal skins, composition similar to Xiangpi. ShengjiXiangpiGaoyao can regulate the growth factor whether the expression has scheduling and cooperativity.