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自身免疫性肝炎的治疗进展

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摘要 自身免疫性肝炎(autoimmune hepatitis,AIH)是一种病因未明的以血清转氨酶增高、高丙种球蛋白血症、自身抗体阳性、界面性肝炎为特点的慢性炎症性肝脏疾病,呈全球范围分布,男女发病率比约为1:3.6[1].其发病机制目前尚不清楚,普遍认为与遗传背景、环境相关.如不给予治疗,5年死亡率约80%[1].有效的治疗可使病情迅速缓解并明显改善患者的预后[2],长期以来在AIH的治疗终点、复发再治疗、疗效不佳的处理及特殊人群的治疗等方面存在诸多问题,随着对AIH认识的不断加深,近年在以上方面取得了一定的进展,笔者就AIH的治疗作一综述.
作者 邹凤 任红
出处 《中国医师杂志》 CAS 2015年第11期1758-1760,共3页 Journal of Chinese Physician
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参考文献22

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