癫癎持续状态病理学研究进展

Research progress on pathological changes of brain caused by status epilepticus

癫癎持续状态为病死率和病残率较高的中枢神经系统常见急危重症,其引起的脑损伤严重程度是影响患者预后的重要因素。从癫癎持续状态诱发的脑组织病理改变角度结合分子水平加以研究,有望揭示其脑损伤机制,为探索癫癎持续状态新的预测与治疗方法提供理论依据。

Status epilepticus（SE） is a common neurological emergency with high disability and mortality rates. The degree of brain injury after SE is a key factor related to the prognosis of patients. The specific mechanism of brain injury after SE could be studied by combining pathological changes and molecular level changes. This paper summarizes the research progress of SE pathology and the underlyin gmechanism to provide a theoretical basis to explore new therapies and diagnostic methods of SE.