老年人缺血性结肠炎临床特征及与中青年患者对比分析

Evaluation of clinical features of ischemic colitis： comparison between young and elderly patients

目的探讨缺血性结肠炎（IC）老年患者的临床特征及易患因素。方法将87例IC患者分为老年组（〉160岁）和中青年组（〈60岁），对其临床资料进行回顾性对比分析，用Logistic回归分析方法研究与Ic相关的危险因素。结果腹痛是Ic患者最常见（95．4％）的临床表现；病变主要累及降乙状结肠；老年组白细胞计数及乳酸脱氢酶浓度高于中青年组（P〈0．05），接受手术治疗及出现并发症的患者多于中青年组（P〈0．05）；便秘及血管／血流动力学异常相关疾病是老年IC发病独立的危险因素。结论老年Ic患者的临床表现和内镜特点与中青年人相似。但老年IC患者病情更加严重，更易出现并发症。便秘及血管／血流动力学异常相关疾病是老年Ic发病独立的危险因素。

Objective To investigate the clinical features and risk factors of ischemic colitis（IC） of elderly. Methods A retrospective analysis was performed in 87 patients with IC in our bospital. They were divided into two groups（ ≥60 and 〈60 years old） and clinical data was compared between the two groups. Logistic regression analysis was used in study of risk factors associated with IC. Results Abdominal pain（95.4% ） was the most common clinical manifestation of patients with IC. Colonoscopy of most patients showed lesionsmainly occurred in descending and sigmoid colon. In laboratory data,leukocyte count and lac- tate dehydrogenase were significantly greater in elderly group（ P 〈 0.05）. Surgical treatment and complica- tions were more in elderly group （ P 〈 0.05 ）. Constipation and disease associated with vasctdar/hemody- namic abnormality were independent risk factors for elderly-onset IC. Conclusion Clinical and endoscop- ic manifestations of elderly group are similar to those of young group. For elderly patients with IC, severe IC and complications are more common than that in young group. Constipation and disease associated with vaseular/hemodynamie abnormality are independent risk factors for elderly-onset IC.