痛风知识教育对2型糖尿病合并高尿酸血症患者的临床效果

Clinical effect observation of gout knowledge education on type 2 diabetes patients with hyperuricemia

目的探讨在2型糖尿病合并高尿酸血症患者中开展痛风知识教育的临床效果。方法选取2型糖尿病合并高尿酸血症患者118例,随机分为观察组、对照组各59例,对照组予糖尿病教育,观察组予糖尿病教育联合痛风知识教育,随访6个月。在随访前及结束时监测生化指标。结果随访6个月后,观察组与对照组相比,血尿酸水平(398.18μmol/L vs445.83μmol/L)、甘油三酯(1.64 mmol/l vs 2.16 mmol/L)、低密度总胆固醇(2.81 mmol/L vs 3.20 mmol/L)明显下降,高密度脂蛋白胆固醇(3.22 mmol/l vs 1.26 mmol/L)明显升高,差异均有统计学意义(P<0.05)。结论在2型糖尿病合并高尿酸血症患者中开展痛风知识教育,可以产生明显降低血尿酸水平的效果,从而改善代谢紊乱。

[Objective] To investigate the clinical effects of gout knowledge education on type 2 diabetes patients with hyperuricemia.[Methods] 118 cases of type 2 diabetes patients with hyperuricemia were selected and randomly divided into control group and observation group, 59 cases in each group. The control group was given diabetes education and the observation group was given diabetes and gout education. All cases were followed up for 6 months. At the start and the end of follow-up, the biochemical indexes were monitored.[Results]After 6 months of follow-up, observation group compared with control group, the levels of serum uric acid（398.18 μmol/L vs 445.83 μmol/L）, TG（1.64 mmol/L vs 2.16 mmol/L） and LDL-C（2.81 mmol/L vs 3.20mmol/L） decreased significantly, HDL-C（3.22 mmol/L vs 1.26 mmol/L） increased significantly（all P〈0.05）.[Conclusion]Carrying out gout education in type 2 diabetes patients with hyperuricemia can significantly reduce the level of serum uric acid and improve the metabolic disorders.