右美托咪定在全麻无痛气管镜中的运用探讨

Application of dexmedetomidine in painless bronchoscopy by general anesthesia

目的分析右美托咪定复合小剂量丙泊酚在无痛纤支镜检查中的临床价值。方法选取我院进行无痛纤支镜检查患者103例,将患者分为两组,分别采用右美托咪定复合小剂量丙泊酚(右美组)和丙泊酚复合小剂量芬太尼组(常规复合麻醉组),对右美组和常规复合麻醉组患者的麻醉效果、呼吸频率、心率、平均动脉压、末梢指脉氧浓度和不良反应进行观察和对比。结果右美组与常规复合麻醉组在麻醉效果的术后唤醒时间比较明显缩短,差别存在统计学意义(P<0.05);右美组术中和苏醒后即刻平均动脉压和指脉氧饱和度要显著优于对照组(P<0.05);右美组的不良反应发生率低于常规组(P<0.05)。结论右美托咪定复合小剂量丙泊酚能够安全、有效地提高无痛纤支镜的麻醉效果。

Objective To analyze the clinical value of dexmedetomidine combined with propofol in painless fibrobronchoscopy. Methods 103 patients who conducted painless fibrobronchoscopy were randomly divided into two groups according to the way of therapy. The group A was given dexmedetomidine combined with propofol,and the group B was given fentanyl combined with propofol. Their effect of anesthesia,haemodynamics,adverse reaction and mean arterial pressure were observed. Results The time of awaken after painless fibrobronchoscopy was shorter in the group A than in the group B（ P 〈0. 05）. MAP and SPO2% were higher in the group A than in the group B（ P 〈0. 05）. The incidence of adverse reaction was lower in the group A than in the group B（ P 〈0. 05）. Conclusion Dexmedetomidine combined with propofol can improve the effect of painless fibrobronchoscopy safely and effectively.